How Sgot Is Determinant Of Health Of Liver, Heart And Human Body Muscles?
SGOT is very vital medical test in certain diseases.Generally it is said to be the marker of general health of liver.But it is not true or false notion see how?
Sgot is known by various names such as
Aspartate transaminase (AST),
aspartate aminotransferase
The abbreiated form SGOT is commonly used in medical world.Its full form is glutamic oxaloacetic transaminase (SGOT).It is an important enzyme in amino acid metabolism.AST or SGOT is found in the liver, heart, skeletal muscle, kidneys, brain, and red blood cells, and it is commonly measured clinically as a marker for liver health But it is not a true marker of health of liver as it is not exclusively found in liver.
Aspartate transaminase catalyzes the interconversion of aspartate and α-ketoglutarate to oxaloacetate and glutamate.
What does high SGOT in a liver function test mean?
LFT orliver function test or SGOT is done to detect, diagnose, evaluate and monitor the presence of liver disease and/or damage to the liver tissues..There are a innumerable different medical conditions and damage that can affect the liver.liver disease may have sometimes no symptoms, so testing is vital.The SGOT (serum glutamic-oxaloacetic transminase) or AST test, actually, measures the amount of a protein enzyme called glutamic-oxaloacetic transaminase occurring in human blood of the patient.This enzyme is normally found in the liver, heart muscles, muscles, bones and red blood cells.When these cells sustain damage or some severe injury, they release this protein enzyme into your blood.so blood level of SGOT becomes elevated or raised.In a normal human being its normal value is 5-15 units per litre but in certain cases it may be as high as 800
SGOT levels are measured to see how our internal organs such as liver, kidney, heart, pancreas, muscles and red blood cells are functioning, are they in health state or damaged state.
An abnormal high level of blood of SGOT shows the extent of damage to liver and muscles of body.
Causes for a high elevated SGOT level may include infection, viral hepatitis, mononucleosis, gallbladder disease, the presence of toxins from drugs or adverse effects of chemicals and drugs or alcohol and various types of cancers.It may also indicate or reveal muscle damage from a fall or injury, or a muscle disease such as polymyositis or muscular dystrophy.And it can indicate problems with human internal organs such as kidneys, heart or pancreas, or a breakdown of red blood cells.one common cause for elevated SGOT are certain chemical drugs to name some such as cholesterol-lowering drugs, anti-inflammatory, anti-fungal medications and some antibiotics (erythromycin) etc No patient goes to get the SGOT test done voluntarily but its elevated levels are revealed during the course of some serious illness.One more enzyme similar to SG PT is SGOT.whereSGOT is elevated the SGPT is also raised.
The normal value of SGOT - Serum Glutamic Pyruvic Transaminase is 5-55 units per litre
SGPT - Serum Glutamic Pyruvic Transaminase
normal: 5-55 U/ml
Some patients have constitutionally elevated SGOT level on each and every blood test .they undertake in some patients this may always remain above normal limits say above 180..It has been observed in some cases that the offspring of parents or mother also may have elevated level of his/her son or daughter, In one case it was unusually high in the son delivered by a mother.It was 500ut / ml.The infant has no other ugly medical symptom and was in good health from ever aspect.Both mother and son tested negative for any type of hepatitis.
An elevated SGOT usually is a reflection of damage to liver cells.Hepatitis due to virus or drugs is the most likely cause.A value high above 200ut/ml would probably not be due to alcohol-induced liver damage.The following are the medical conditions in which SGOT may be raised.
Acute kidney failure
Cirrhosis (scarring of the liver)
Heart attack or some previous heart attack history
Ischemic heart damage history.
Hemochromatosis
Hemolytic anemia
Viral Hepatitis
Lack of blood flow to the liver (liver ischemia
Addiction to alcohol.
Muscle damage or injury due to heavy unusual exercise
Rhabdomylosis .